اطلاعات لازم برای سفارش پپتید (اردیبهشت 1397)

Synthetic peptides are:

  • Easy to make, easy to characterize, fast, parallel synthesis
  • Unnatural AA’s and other variations of structure are feasible
  • Can create totally new structures (e.g. “mimotopes”, MAPs, cyclics etc.)
  • Can make mixtures or use prediction methods
  • Can be cheaper than alternatives
  • Can patent the application

Application – Immunology: 

Epitope mapping – B cells and T cells
Different types of T cell
Analoging for fine specificity of recognition
Predictive methods not reliable but can help narrow down the choices

Application – Biochemistry
Enzymology – peptidases and proteases. Looking for active sites or substrates/analogs
Using antipeptide antibodies for inhibiting biological activity
Antipeptide antibodies for protein tracing, e.g. in Proteomics

Application – Physiology, Pharmacology, Developmental Biology
Bioactive hormones and analogs
Antipeptide antibodies for protein tracing
Antipeptide antibodies for screening for protein modifications

Application – Vaccine Research
Immunization with peptides to create a protective response
Monitoring of vaccine responses – antibodies and T cells

Application – Drug Development
Novel peptides from libraries
More-bioactive analogs of known bioactive peptides

Application-Diagnostics
Immunodiagnosis with dominant epitopes: antibodies and T cells
Testing for protective immunity, or for pathology (autoimmunity and allergy)

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